Boys:
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Lycaon Paris Hector + Andromache + Helenus Deiphobus Antiphus Polites + ? Polydorus Hipponous Troilus Laocoon + ?
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Astyanax Polites 2 sons
Girls:
Cassandra Polyxena Ilione + Polymnestor Creusa + Aeneas Laodice
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2 children
King Priam had 50 sons, 12 daughters, and 42+ bastard children. I've just listed the most famous.